Sb-modified Mn/TiO2 catalyst synthetized by sol-gel method exhibited outstanding performance in simultaneous Hg-0 oxidation and NO reduction under SCR conditions at low temperature. NO removal (>90%) and Hg-0 oxidation (>80%) were simultaneously obtained over MnSb/TiO2-0.25 catalyst in 200-300 degrees C with a GHSV of 54,000 h(-1). Moreover, MnSb/TiO2-0.25 catalyst exhibited excellent tolerance to SO2 and H2O. Characterization results suggested that the well-dispersed Mn, Sb and Ti species, along with the enriched Mn4+ and surface oxygen species on Mn-Sb/TiO2 -0.25 catalyst should play a critical role in its excellent catalytic performance. The formed HgO had little inhibition effect on NO reduction over MnSb/TiO2-0.25 catalyst. And the coexistence of NO and O-2 has a promotion effect on Hg-0 oxidation, while NH3 exhibited an inhibition effect on oxidation of Hg-0. In SCR reaction process, the Hg-0 oxidation efficiency was suppressed, but this effect could be basically eliminated by using a relatively low GHSV value. Thus using MnSb/TiO2-0.25 for simultaneous Hg-0 oxidation and NO reduction in SCR reactor may be workable in coal-burning power plants. Based on the results of experiments and characterizations, the mechanism of synchronous removal of Hg-0 and NO on MnSb/TiO2-0.25 catalyst could be described as:Hg-0(ad)+O-alpha(O-beta)-> HgO(ad), NO(g)+NO2(ad)+NH3(ad)-> N-2+H2O.