Strain rate has significant effect on mechanical behavior of the thermoset polymers. The rate sensitivity is more complicated for thermoset nanocomposites, which compose of two quite different types of materials. Nanofiller-reinforced epoxy resin is widely used in the industry. In the present work, epoxy resin is reinforced by 0.05 to 0.7 wt% nanographene oxide (GO). The strain rate sensitivity of the fabricated nanocomposites is investigated through compressive test carried out at the strain rates of 0.001-1,900 s(-1). The stress-strain curves of the nanocomposites indicated considerable difference between the low-strain and high-strain-rate responses of the specimens. The results showed that the compressive strength of the nanocomposites was improved by more than 100% at high strain rates with respect to the low strain rates. Also, the addition of nano-GO had influence on compressive strength enhancement but not as significant as the effect of strain rate. It was observed that the effect of GO was less important for higher strain rates. The experimental compressive strength and modulus of elasticity of the nanocomposites were casted in empirical relations for low and high strain rates for various filler weight percentages. Scanning electron microscopy was also used to examine the quality of GO dispersion. POLYM. ENG. SCI., 59:1636-1647 2019. (c) 2019 Society of Plastics Engineers