Knowledge of fire and explosion-related properties of substances including flammability limits, minimum ignition energies, and flash points are critical in process safety research. However, conducting experimental measurements to determine these properties is often time consuming and hazardous. The recent development of quantitative structure-property relationship (QSPR) analysis provides accurate and reliable predictions of such target properties. In this review, upper and lower flammability limits and temperatures (UFL, UFLT, LFL, and LFLT), minimum ignition energy (MIE), auto-ignition temperature (AIT), flash point (FP), and other related properties are selected for investigation. Developments of QSPR methods within the past decade to predict each of these properties are summarized and examined. These developments serve to address the increasing need for improved fire and explosion risk assessment methods in the process industries. (C) 2019 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.