This paper presents experimental results on the effect of various operating parameters on the synthesis of gas hydrates by a method based on the self-organizing process of boiling-condensation of a hydrate-forming gas in the volume of water. A series of experimental studies were carried out under various conditions, and optimal conditions that affect the process of hydrate formation were determined. The influence of the water column height and the boiling intensity of the hydrate-forming gas on the hydrate formation process is estimated. Freon 134a was used as a hydrate-forming gas in the studies.