The supercritical CO2 foaming process is a preferable way to treat deserted SF-3 propellants and solves problems of environmental pollution and waste of resources related to conventional treatment methods, and this process is an environmentally friendly method. In this paper, the effect of process conditions, including the immersion time of deserted SF-3 propellants in the supercritical CO2 fluid, on the appearance of SF-3 propellants and detonation performance of the perfusion explosive made from SF-3 propellants are mainly studied. The results show that the diameter of foamed SF-3 propellants increases with the immersion time when the immersion time is less than 60 min. When the immersion time is 60 min, the performance of the perfusion explosive made from foamed SF-3 propellants is the best. The highest detonation velocity is 6683 m s(-1), and the corresponding shock wave energy is 1.02 kJ g(-1). When the immersion time is more than 60 min, the detonation velocity and the shock wave energy of the perfusion explosive made from foamed SF-3 propellants decreases with the increase of the immersion time.