Utilizing egg white proteins and peptides as functional materials is very attractive, because they are available at low cost. Ovalbumin (OVA) is a major globular protein in egg white. Previously, we focused on the peptide fragment corresponding to the helix A region of OVA (pN1-22, acetyl-GSIGAASMEFCFDVFKELKVHH) and explored its function. Here, we report nanoparticle formation of this OVA-derived peptide and its ability to prevent the aggregation of pathogenic proteins.