This paper studies input-to-state stability (ISS) of general nonlinear time-delay systems subject to delay-dependent impulse effects. Sufficient conditions for ISS are constructed by using the method of Lyapunov functionals. It is shown that, when the continuous dynamics are ISS but the discrete dynamics governing the delay-dependent impulses are not, the impulsive system as a whole is ISS provided the destabilizing impulses do not occur too frequently. On the contrary, when the discrete dynamics are ISS but the continuous dynamics are not, the delayed impulses must occur frequently enough to overcome the destabilizing effects of the continuous dynamics so that the ISS can be achieved for the impulsive system. Particularly, when the discrete dynamics are ISS and the continuous dynamics are also ISS or just stable for the zero input, the impulsive system is ISS for arbitrary impulse time sequences. Compared with the existing results on impulsive time-delay systems, the obtained ISS criteria are more general in the sense that these results are applicable to systems with delay dependent impulses while the existing ones are not. Moreover, when consider time-delay systems with delay-free impulses, our result for systems with unstable continuous dynamics and stabilizing impulses is less conservative than the existing ones, as a weaker condition on the upper bound of impulsive intervals is obtained. To demonstrate the theoretical results, we provide two examples with numerical simulations, in which distributed delays and discrete delays in the impulses are considered, respectively.