The uncertain role of the natural gas infrastructure in the decarbonized energy system and the limitations of hydrogen blending raise the question of whether natural gas pipelines can be economically utilized for the transport of hydrogen. To investigate this question, this study derives cost functions for the selected pipeline reassignment methods. By applying geospatial hydrogen supply chain modeling, the technical and economic potential of natural gas pipeline reassignment during a hydrogen market introduction is assessed. The results of this study show a technically viable potential of more than 80% of the analyzed representative German pipeline network. By comparing the derived pipeline cost functions, it could be derived that pipeline reassignment can reduce the hydrogen trans- mission costs by more than 60%. Finally, a countrywide analysis of pipeline availability constraints for the year 2030 shows a cost reduction of the transmission system by 30% in comparison to a newly built hydrogen pipeline system. (C) 2020 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.