The characterization of tetramethylethylenediamine + water mixtures in relation to different physicochemical properties (density, viscosity, speed of sound, and surface tension) over the whole range of composition is reported in the present work. Other derivative properties such as molar excess volume and isentropic compressibility coefficient were determined in order to explain the mixture behavior. Experimental measurements were done over the temperature range T = (293-323) K. This type of characterization has an important influence upon process modelization in chemical engineering.