In this work is presented a facile method for the elaboration of starch-chitosan films with functionalized particles of titanium dioxide. The chemical modification of the nanoparticles allows to improve the mechanical properties of the film itself. The films containing the TiO2 functionalized with the alkoxysilane presented an improvement in the tensile strength of 33%. Also, the insertion of silver nanodots reinforces the antimicrobial properties of the starch-chitosan films. This method of fabrication of biodegradable films represents an excellent green choice for possible applications as food packaging due to their mechanical properties.