In the present work, experimental studies were conducted to examine the gas-slurry interfacial shear stress and frictional pressure drop in the presence and absence of surfactant in a rectangular slurry column. A novel mechanistic model has been proposed by considering the energy dissipation rate because of bubble formation, a slip of gas-slurry interface, and the wetting of a thin liquid layer with the column wall. A comprehensive investigation was carried out to enunciate the effect of particle loading, particle size, bubble size, and surfactant on the frictional pressure drop and bubble-slurry interfacial shear stress. Generalized empirical coirelations were also developed based on the dynamic variables, geometric variables, and physical properties of the system. (C) 2020 Elsevier B.V. All rights reserved.