In this study, a novel method combining microplate fluorescence imaging (FI) and high-throughput screening (HTS) technology was applied to screen and evaluate the multicomponent metal (Zn, Cd, Ni) sulfides-modified g-C3N4 with high-activity photocatalytic performance. Glass screen printing was creatively used in preparing a photocatalytic reaction microplate containing 225 independent micro-reaction chambers (mu RCs) as experiment carriers. A photocatalyst chip comprising 225 ZnxCdyNi1-x-yS/g-C3N4 multicomponent photocatalysts was made via chemical ink-jet printing (IJP) technology, at last 23 high-efficiency M3S/g-C(3)N(4)were screened out from the photocatalyst chip by the optical density (OD) method. Graphic