Design and synthesis of low cost and efficacious industrial catalyst for the oxidation of styrene has been an important research project. Herein, ZSM-5 zeolite containing tetrahedral vanadium (V) and Brensted add sites (V-H-ZSM-5) was prepared, and identified by characterizations such as XRD, SEM, UV-vis, NH3-TPD, H-2-TPR N-2-adsorption/desorption and FTIR. V-H-ZSM-5 performed extremely enhanced catalytic activity for the oxidation of styrene with 30% H2O2 at 40 degrees C. Moreover, in-situ FTIR spectrum was used to investigate the catalytic mechanism. The results demonstrate that Brensted add site could not only increase the adsorption concentration of styrene in the micropores of V-H-ZSM-5 via the n complex interaction between double bond of styrene and Brensted acid sites, but also increase the oxidation potential of H2O2. The synergetic action of tetrahedral vanadium (V) and Brensted add enhanced the catalytic activity for the oxidation of styrene with 30% H2O2 Impressively, V-H-ZSM-5 performed high reusability within five runs at a low reaction temperature (40 degrees C) for the first time. (C) 2020 The Chemical Industry and Engineering Society of China, and Chemical Industry Press Co., Ltd. All rights reserved.