Effects of hydrodynamics and surface chemistry properties on attachment interaction between low-rank coal particles and bubbles were investigated. The surfactants such as 2-ethyl hexanol, dodecyl amine hydrochloride, and sodium dodecyl sulfate were added to change the surface chemistry of low-rank coal particles. The relationship between induction time and bubble Reynolds number showed an index relationship. The induction time would become shorter while the energy barriers between particles and air bubbles are easily overcome with bubble Reynolds number increase. Therefore, the hydrodynamics and surface chemistry properties had a significant effect on the attachment interaction between low-rank coal particles and bubbles.