Experiments were conducted in an enclosure with the same overall dimensions as a 40-foot ISO container to study the vented hydrogen-air deflagrations. This work focuses on the effects of hydrogen concentration, ignition location and obstacles on the overpressure and the structural response of the container wall. For center ignition, three overpressure peaks, which resulted from the vent opening, Helmholtz oscillation and acoustic oscilla- tion, respectively, were recorded inside the container without obstacles. However, with the increase of hydrogen concentration, the third overpressure peak disappears when the obstacles are added in the container. Unlike center ignition, only two overpressure peaks were observed for back ignition. Due to the difference in reactivity of hydrogen-air mixture, the first overpressure peak is generated by the vent burst for low hydrogen concentration, or the venting of flame for high hydrogen concentration. The overpressure induced by the flame-acoustic interaction was not monitored with the increase of the hydrogen concentration and the installation of obstacles for back ignition. The overpressure for back ignition is more influenced by the obstacles than that for center ignition, when hydrogen concentration is larger than 12%. The displacement-time curves share similar trends with the pressure-time curves. The first peak displacement changes linearly with the corresponding first peak overpressure. However, the displacement caused by the second over-pressure peak is significantly increased, especially for high hydrogen concentration and back ignition in the case with two obstacles. (C) 2020 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.