Anodic oxidation based on PbO2 anode has been demonstrated as the feasible approach for the decontamination of organic pollutants; however, the performance of this process is hindered by its ordinary electrochemical activity and relatively low stability. In this study, we fabricated an efficient Ti/TiO2-RNTs/Sb-SnO2/PbO2-ND electrode with electrochemically reduced TiO2 nanotubes as the interlayer and nano-diamond as the dopant. As compared with other electrodes, the constructed Ti/TiO2-RNTs/Sb-SnO2/PbO2-ND exhibited higher oxygen evolution overpotential, larger active area and less charge transfer resistance. Thus, the average current efficiency of 30% could be attained at 120 min with TiO2-NTs/Sb-SnO2/PbO2, which was 1.5 times higher in comparison with the typical Ti/Sb-SnO2/PbO2 electrode. It was found that the removal efficiency of COD could be increased from 49% to 69% after 120 min treatment in the presence of 10 mM Cl-1 in the electrolyte. After 6 h of electrolysis, 74% of TOC was removed and 31% and 22% of initial N was transformed into NH4+ and NO3- ions, respectively. And oxalic acid, glyoxylic acid, malonic acid and acetic acid were identified quantitatively as the intermediate products. Finally, it was estimated that the accelerated service life of Ti/TiO2-RNTs/Sb-SnO2/PbO2-ND electrode was approximately three times of Ti/Sb-SnO2/PbO2 electrode. Generally, this study is of great interest for the engineering community to design an efficient electrode material for the wastewater treatment. (C) 2020 Elsevier Inc. All rights reserved.