An experimental study and detailed kinetic modeling of characteristics of the matrix conversion of a methane-oxygen mixture with the addition of hydrogen, carbon monoxide, synthesis gas, and steam have been carried out. It has been shown that the most significant effect on the product composition is provided by the admixture of steam, which reduces the yield of acetylene and at the same time increases the H-2/CO ratio. The kinetic simulation results appear to agree well with the experimental data obtained.