The review is devoted to studying the possibilities of using supercritical fluids as a reaction medium in the chemical and petrochemical industries, which will solve the urgent problem of replacing traditional toxic, explosive, and fire hazardous organic solvents with environmentally friendly "green" solvents. A comparative analysis of scientific and technological achievements in the application of supercritical fluid technologies (SCF technologies) in widely used petrochemical processes, such as oxidation, hydrogenation, hydroformylation, polymerization, metathesis, and other SCF technologies, have a commercial focus; they have a number of potential competitive advantages and have been implemented or planned for industrial implementation in the near future.