화학공학소재연구정보센터
Process Biochemistry, Vol.94, 126-135, 2020
Systematic and validated techniques for the detection of ovarian cancer emphasizing the electro-analytical approach
Ovarian cancer refers to a cancer that forms inside or on the surface of an ovary. It results in the abnormal growth of cells that can attack or spread to other parts of the body. According to the reports, early detection can minimize the risk of mortality and can lead to effective management of the disease. Though, recently used methods can only enable to detect the cancer at an advanced stage. Therefore, rapid and effective approaches for detecting ovarian cancer are urgently in demand. Researchers are fascinating towards an effective portable and early detection technique for the diagnosis of ovarian cancer. Biosensors are best alternative to afore mentioned demand as they are designed for detecting a particular biotic analyte by converting a biological entity such as antibody, blood, cell, etc. into an electronic signal that can be measured and analyzed. Biosensor technology can accommodate rapid and precise diagnosis of cancer-related cells and deliver an improved approach for making them sensitive and specific. Furthermore, choice of biomarkers also plays an important role in determining the stage of cancer. This review summarizes the classification of ovarian cancer, biomarkers and techniques employed for the detection of ovarian cancer. Besides, some of the future outlooks of bio sensing technology are also discussed.