PrSrCo(1-x)CuxO(4+delta) (x = 0.0, 0.1, 0.3, 0.5) are synthesized by solid-state reaction method. The effects of Cu2+ doping on electrical conductivity, thermal expansion, oxygen diffusion properties and oxygen reduction reaction (ORR) activity are investigated. PrSrCo1-xCuxO4+delta oxides crystallize in a single-phase tetragonal structure with I4/mmm space group. Partial substitution Co3+ by Cu2+ results the increase of electrical conductivity and decrease of thermal expansion coefficient. Introducing Cu2+ promotes the formation of interstitial oxygen, accelerates the kinetics of oxygen transport, and significantly improves the electrocatalytic activity of ORR. The lowest area specific resistance (ASR) value of 0.08 U cm(2) is obtained for the PrSrCo0.7Cu0.3O4+delta cathode at 700 degrees C in air. The ORR mechanism study demonstrates that Cu-doping (30%) promotes the charge transfer process. The reaction rate control step on PrSrCo0.7Cu0.3O4+delta cathode is the dissociation and surface diffusion process of adsorbed molecular oxygen. (c) 2020 Elsevier Ltd. All rights reserved.