Zearalenone (ZEN) is a severe contaminant mycotoxin found worldwide. Our previous results indicate thatBacillus velezensisA2 isolated from ZEN-contaminated crop soil can degrade ZEN. Here, we present the complete genomic sequence ofB. velezensisA2 (the Genbank accession number: CP053717), which contains 3,929,218 bp in the chromosome, has a GC content of 46.5%, and contains the encoded ZEN-degrading enzyme gene. The complete genomic sequence can provide a genomic basis for a series of A2 biotechnology applications as an effective method of degrading ZEN.