Acidic SBA-15 modified by molybdenum oxide has been synthesized. These materials were characterized by low nitrogen adsorption/desorption, Fourier transform infrared spectroscopy, transmission electron microscopy, NH3 temperature-programmed desorption, NMR, and XRD techniques. In this work, the activity of acidic Al-SBA-15 modified with molybdenum oxide in the oxidation of sulfur-containing compounds was investigated for the first time. It was shown that the SBA-15 support containing aluminum allows to significantly increase the catalytic activity of molybdenum oxide. The main factors affecting the process consisting of catalyst dosage, temperature, reaction time, oxidant dosage were investigated in detail. In the presence of synthesized catalysts, dibenzothiophene can be completely oxidized in 30 min. These catalysts retain their activity in DBT oxidation for 10 cycles.