The study on ethylene glycol electro-oxidation has attracted great attention due to it as a key anode reaction in direct ethylene glycol fuel cells (DEGFCs). In this paper, layered WS2 nanosheets are grown on a carbon cloth (CC) and then act as a three-dimensional (3D) flexible electrode for depositing Pt nanoparticles on WS2/CC by the electrodeposition technique. The as-prepared 3D Pt-WS2/CC electrode (9931 mA mg(p)(t)(-)(1)) shows 4.84 and 17.3 times enhanced electrocatalytic activity toward ethylene glycol (EG) electrooxidation, compared with Pt direct deposited CC electrode (Pt/CC, 2050 mA mg(p)(t)(-)(1)) and commercial Pt/C electrode (575 mA mg(p)(t)(-)(1) ), respectively. Interestingly, when 3D Pt-WS2/CC electrode is exposed to visible light irradiation, the forward sweep current density of EG oxidation is increased to 16 980 mA mg(p)(t)(-)(1) , which is 29.5 times that of the Pt/C electrode under ambient condition. The cycling stability and chronoamperometric results also indicate that the electrocatalytic stabilities of 3D Pt-WS2/CC electrode are improved by visible light illumination. The excellent electrochemical performances and low-cost characteristics make these 3D flexible nanocomposite electrodes have great prospects in traditional electrocatalytic reactions with the aid of solar light illumination.