Numerus research studies focus on replacing scarce noble metals by non-noble transition metals in solid catalysts. The (de)hydrogenation function in bifunctional catalysts for hydroisomerization and hydrocracking of alkanes is usually performed by a precious metal such as Pt, or a metal sulfide such as MoS2. In this study, we investigated the possibility of replacing Pt with a non-sulfided MoOx catalyst in combination with a mesoporous solid acid for the hydroisomerization of n-heptane. MoOx particles size as well as the preparation techniques were varied in order to identify the Mo active phase for (de) hydrogenation. We demonstrated that an optimized non-precious metal MoOx catalyst can perform similarly to its Pt counterpart in the n-heptane conversion when used in combination with a mesoporous solid acid. (C) 2020 Published by Elsevier Inc.