Binary mixtures of 2-(2-methoxyethoxy)ethanol and alcohols were characterized in terms of the existence of intermolecular interactions at different temperatures (293.15, 303.15, 313.15, and 323.15) K and at pressure p = 0.1 MPa. The alcohols were methanol, ethanol, propan-1-ol, propan-2-ol, butan- 1 -ol, and butan-2-ol. The study was based on the measurements of densities, speeds of sound, and refractive indices over the entire range of mixture compositions. The obtained data were used to calculate various thermodynamics/deviation properties: excess molar volume, isentropic compressibility, deviation in isentropic compressibility, and deviation in refractive indices. Excess/deviation properties were fitted to the Redlich-Kister equation to estimate the coefficients. The standard deviation of the fit was calculated between the predicted and the experimental quantities to ensure the accuracy of the experimental data.