We explored the electrowetting behavior of a hydrofluoroester solvent, Novec 7100 (Novec), as a liquid droplet on a Au(111) electrode in water (0.05 M KClO4). Comparison with the electrowetting of hexadecane (HD) highlighted the significance of the lower adhesion energy and static friction energy of Novec than those of HD. The electrode potential-dependent contact angle theta of a Novec droplet showed little hysteresis. When potentials were set by means of potential steps, a Novec droplet increased its theta at more positive potentials than the potential of zero charge (pzc) of the Au(111) electrode. We found that the key factor of the electrowetting behavior for Novec is its low adhesion energy and static friction energy. The static friction energy of the oils to the Au(111) electrode surface was evaluated by a comparative analysis of the potential dependence of the interfacial tension at the solid/water interface, Delta gamma(S/W)-E curve, calculated from electrochemical surface charge data and the experimental cos theta-E curve: 2.6 mN/m for HD and 0.95 mN/m for Novec. When Br- was added in the aqueous solution to allow its adsorption on the Au surface surrounding a Novec droplet, the potential of maximum cos theta was shifted to negative. Overall, although the Novec droplet showed a narrower range of theta change than a HD droplet, the Novec droplet seldom got stuck to the surface as far as potential step was used, reflecting the narrower plateau region of theta near the pzc. Also, the specific adsorption of a coexistent anion was a significant factor of theta. This work has featured the significance of a slippy droplet on an electrode surface, giving an impact on the technology of microfluid transportation control by electric potentials.