Wall conditioning in DIII-D is one of the most important factors in achieving reproducible high confinement discharges. For example, the very high confinement mode (VH-mode) was only discovered after boronization, a chemical vapor deposition technique to deposit a thin boron film over the entire surface of the tokamak. In order to evaluate wall conditions and provide a data base to correlate these wall conditions with tokamak discharge performance, a series of nominally identical reference VH-mode discharges (1.6 MA, 2.1 T, double null diverted) were taken at various times during a series of experimental campaigns with evolving wall conditions. These reference discharges have allowed a quantitative determination of how the wall conditions have evolved. For instance, core carbon and oxygen levels in the VH-mode phase remained at historically low levels during the 1995 run year and there was also a steady decrease in the oxygen levels at plasma initiation during this period. We will discuss the long term changes in low Z impurities and the effect of wall conditioning techniques such as boronization and baking on these impurities. In addition, the evolution of the deuterium recycling rates will be discussed.