Based on a hybrid Eulerian-Lagrangian approach, erosion characteristic of membrane tubes in a membrane-assisted fluidized bed reactor is numerically evaluated. The erosion rate of Pd-based membrane is integrated. The influence of hydrogen separation on gas-solid hydrodynamics and erosion characteristics is discussed. The relationship between concentration polarization and membrane tube erosion is examined. The results demonstrate that the maximum wear of Pd-based membrane occurs at the normal angle. The hydrogen separation weakens membrane tube erosion in a fluidized bed. The arrangement of membrane tube locations plays a very important role in tube erosion. The non-uniform hydrogen concentration strengthens the maximum membrane tube wear, especially for the bottom of the fluidized bed reactor. (C) 2020 Elsevier B.V. All rights reserved.