Thermal utilization of meat-and-bone meal (MBM) is subject to stringent regulations that are meant to provide elimination of any potential pathogens. Incineration as well as other possible routes for thermal conversion of MBM are still at the research state. The universal technology was developed that allows to combust various types of waste organic materials, including animal waste, municipal solid waste and sludge, mixed at any ratio with different types of biomass. It provides the possibility to utilize the waste and-biomass fuel blends of up to 90%wt of moisture content, while maintaining the allowable pollutant emissions and soil contamination. This regards mainly NOx, SO2, HCl and VOC. Contrary to the typical large scale grate boilers used for waste burning, the developed operating pilot-scale plant with a capacity of 12 MW offers the complete combustion of MBM, resulting in a flue gas which is proved to be free of flammable gaseous components and sooty particles in slag and fly ash. The thermal decomposition and combustion of waste using this technology ensures thermal conversion of chemical energy contained in waste and biomass. The efficiency of the prototype installation varied between 84.8 and 88.4% depending on the facility load. (c) 2020 Elsevier Ltd. All rights reserved.