Extraction of parishin B and parishin C from Gastrodiae Rhizoma by subcritical water technology

Guozhen Wu; Hongjing Dong; Jia Li; Lanping Guo; Yan Cheng; Yanling Geng; Xiao Wang

Journal of Industrial and Engineering Chemistry, Vol.108, 280-287, April, 2022

DOI10.1016/j.jiec.2022.01.010 Export Citation

Extraction of parishin B and parishin C from Gastrodiae Rhizoma by subcritical water technology

Guozhen Wu^{1, 2}, Hongjing Dong^{1, 3}, Jia Li⁴, Lanping Guo⁵, Yan Cheng^{1, 3}, Yanling Geng^{1, 3}, and Xiao Wang^{1, 3, †}

¹Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Qilu University of Technology, Jinan 250014, China
²School of Pharmaceutical Sciences, Shandong, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
³School of Pharmaceutical Sciences, Qilu University of Technology, Jinan 250355, China
⁴School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan 250355, China
⁵Resource Center of Chinese Materia Medica, State Key Laboratory Breeding Base of Dao-di Herbs, China Academy of Chinese Medical Sciences, Beijing 100700, China

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Subcritical water extraction (SWE) was used to extract bioactive parishin B (PB) and parishin C (PC) from Gastrodiae Rhizoma. Extraction conditions were optimized by Box-Behnken design (BBD) of response surface methodology (RSM). The highest yield of PB was 7.46 ± 0.18 mg/g when the solid/liquid ratio (SLR) was 4.5 mg/mL at an extraction temperature of 118 ℃ and extraction time of 50 min, and the highest yield of PC was 5.27 ± 0.07 mg/g when the SLR was 22 mg/mL at an extraction temperature of 145 ℃ and extraction time of 23 min. Compared with heating reflux extraction the yield of PB was about 1.3 times higher, and that of PC about 2.6 times higher; Compared with ultrasound assisted extraction the yield of PB was about 3 times higher, and that of PC about 6 times higher. Degradation of parishin A by SWE showed that the increasing mechanism of PB and PC mainly attributed to the conversion of PA into PB and PC. This study suggests that SWE was an efficient and green way to extract natural products with greater values.

Keywords:parishin B;parishin C;Subcritical water;Response surface methodology;Extraction

[References]

Elkordy AA, Haj-Ahmad RR, Awaad AS, Zaki Rm, J. Drug Deliv. Sci. Technol., 63 (2021)
Choi YH, Verpoorte R, Curr. Opin. Food Sci., 26, 87 (2019)
Rao MV, Sengar AS, Sunil CK, Rawson A, Trends Food Sci. Technol., 116, 975 (2021)
Liu Y, Gao JL, Peng M, Meng HY, Ma HB, Cai PP, Xu Y, Zhao Q, Si GM, Front. Pharmacol., 9, 24 (2018)
Zhan HD, Zhou HY, Sui YP, Du XL, Wang WH, Dai L, Sui F, Huo HR, Jiang TL, J. Enhnopharmacol., 189, 361 (2016)
Liu ZH, Ma H, Wang WP, Xu SF, Wang L, Shi JG, Wang XL, Acta Pharm. Sin., 51, 743 (2016)
Wang Q, Li ZF, Wang DX, Yang SL, Feng YL, Biomed. Pharmacother, 121, 1 (2020)
Liu ZH, Wang WP, Feng N, Wang L, Shi JG, Wang XL, Acta Pharm Sin. B, 6, 189 (2016)
Shin EJ, Whang WK, Kim SG, Bach JH, Kim JM, Nguyen XKT, Nguyen TTL, Jung BD, Yamada K, Nabeshima T, Kim HC, J. Pharm. Sci., 113, 404 (2010)
Ma FW, Yang XC, Wang R, Y.L. J. Guiyang University (Natural Sciences), 13, 76 (2018)
Tian ZP, Xiao H, Feng SH, Liu DW, Cheng JT, Chen S, Chin. J. Exp. Tradit. Med. Form, 23, 18 (2017)
Li Y, Liu XQ, Liu SS, Liu DH, Wang X, Wang ZM, Molecules, 24, 3159 (2019)
Dahrmoune F, Spigno G, Moussi K, Remini H, Cherbal A, Madani K, Ind. Crop. Prod., 61, 31 (2014)
Gbashi S, Adebo OA, Piater L, Madala NE, Njobeh PB, Sep. Purif. Pev., 46, 21 (2017)
Ko MJ, Cheigh CI, Cho SW, Chung MS, J. Food Eng., 102, 327 (2010)
Bruno P, Murilo MN, Isabel SN, Pedro S, Alexandre P, Suasna B, J. Ind. Eng. Chem., 72, 453 (2019)
Luo XP, Duan YQ, Yang WY, Zhang HH, Li CZ, Zhang JX, Carbohydr. Polym., 157, 794 (2017)
David N, Phillip P, Saravana PS, Jin-Seok P, Byung SC, J. Ind. Eng. Chem., 80, 696 (2019)
Chinese Pharmacopoeia Commission., Pharmacopoeia of the People’s Republic of China, part I Chinese Medical Science and technology press, Beijing, China 59, 2020.

[1] Elkordy AA, Haj-Ahmad RR, Awaad AS, Zaki Rm, J. Drug Deliv. Sci. Technol., 63 (2021)

[2] Choi YH, Verpoorte R, Curr. Opin. Food Sci., 26, 87 (2019)

[3] Rao MV, Sengar AS, Sunil CK, Rawson A, Trends Food Sci. Technol., 116, 975 (2021)

[4] Liu Y, Gao JL, Peng M, Meng HY, Ma HB, Cai PP, Xu Y, Zhao Q, Si GM, Front. Pharmacol., 9, 24 (2018)

[5] Zhan HD, Zhou HY, Sui YP, Du XL, Wang WH, Dai L, Sui F, Huo HR, Jiang TL, J. Enhnopharmacol., 189, 361 (2016)

[6] Liu ZH, Ma H, Wang WP, Xu SF, Wang L, Shi JG, Wang XL, Acta Pharm. Sin., 51, 743 (2016)

[7] Wang Q, Li ZF, Wang DX, Yang SL, Feng YL, Biomed. Pharmacother, 121, 1 (2020)

[8] Liu ZH, Wang WP, Feng N, Wang L, Shi JG, Wang XL, Acta Pharm Sin. B, 6, 189 (2016)

[9] Shin EJ, Whang WK, Kim SG, Bach JH, Kim JM, Nguyen XKT, Nguyen TTL, Jung BD, Yamada K, Nabeshima T, Kim HC, J. Pharm. Sci., 113, 404 (2010)

[10] Ma FW, Yang XC, Wang R, Y.L. J. Guiyang University (Natural Sciences), 13, 76 (2018)

[11] Tian ZP, Xiao H, Feng SH, Liu DW, Cheng JT, Chen S, Chin. J. Exp. Tradit. Med. Form, 23, 18 (2017)

[12] Li Y, Liu XQ, Liu SS, Liu DH, Wang X, Wang ZM, Molecules, 24, 3159 (2019)

[13] Dahrmoune F, Spigno G, Moussi K, Remini H, Cherbal A, Madani K, Ind. Crop. Prod., 61, 31 (2014)

[14] Gbashi S, Adebo OA, Piater L, Madala NE, Njobeh PB, Sep. Purif. Pev., 46, 21 (2017)

[15] Ko MJ, Cheigh CI, Cho SW, Chung MS, J. Food Eng., 102, 327 (2010)

[16] Bruno P, Murilo MN, Isabel SN, Pedro S, Alexandre P, Suasna B, J. Ind. Eng. Chem., 72, 453 (2019)

[17] Luo XP, Duan YQ, Yang WY, Zhang HH, Li CZ, Zhang JX, Carbohydr. Polym., 157, 794 (2017)

[18] David N, Phillip P, Saravana PS, Jin-Seok P, Byung SC, J. Ind. Eng. Chem., 80, 696 (2019)

[19] Chinese Pharmacopoeia Commission., Pharmacopoeia of the People’s Republic of China, part I Chinese Medical Science and technology press, Beijing, China 59, 2020.