A brief review of oxidation reactions catalyzed by zeolite ship-in-a-bottle complexes is presented. The encapsulation of V(O)SALEN (SALEN = bis(salicylaldehyde)ethylenediimine) in zeolite NaY via the flexible ligand method is described. V(O)SALEN-NaY was found to be an effective catalyst for the room temperature epoxidation of cyclohexene using t-butylhydroperoxide (t-BOOH) as the oxidant. The preparation of zeolite NaX in the presence of RuF(16)Pc (F(16)Pc = perfluorophthalocyanine) also results in occluded metal complex. RuF(16)Pc-NaX has been shown to be an active catalyst for the room temperature oxidation of alkanes using t-BOOH as the oxidant.