The paper presents a new approach to a low-pressure fiber-optic sensing employing pressure-induced deformation effects occurring in twisted nematic LC cells. This method is particularly suitable for measurement of pressures up to 2 MPa and utilizes strong rotatory power occurring in chiral nematic liquid crystals. The effect manifests itself in rotation of linear polarization of light coming through a LC cell and resides in detecting changes in helicoidal pitch of a chiral nematics under the pressure-induced deformation of the cell. Results indicate that this method of hydrostatic pressure measurement offers high response to pressure with reduced temperature sensitivity and, depending on the on the specific LC materials and on geometry of the LC cell used, can be pre-set for a required range of pressure.