Blends of a thermotropic liquid crystalline polymer (LCP) with poly(ether imide) (PEI), poly(ether ether ketone) (PEEK), polysulfone (PSF) and polyarylsulfone (PAS) prepared by screw extrusion have been investigated by differential scanning calorimeter and dynamic mechanical thermal analysis. From the measured glass transition temperature (T-g) and specific heat increment (Delta C-p) at the T-g, it appears that the LCP dissolves more in the PEI- and PEEK-rich phases than does the PEI and PEEK in the LCP-rich phase. From the DSC study of PSF-LCP and PAS-LCP blends, the T-g(PSF) and T-g(PAS) of each blends are almost constant with blend composition. Therefore, it is concluded that PSF and PAS are immiscible with LCP. The polymer-polymer interaction parameter (chi(12)) and the degree of disorder (y/x(1)) of LCP have been investigated using the Flory lattice theory in which the anisotropy of LCP is considered. The chi(12) values have been calculated from the T-g data and found to be 0.181+/-0.004 at 593 K for the PEI-LCP blends and 0.069+/-0.006 at 623 K for the PEEK-LCP blends. Using the previously presented method, the chi(12) and y/x(1) in partially miscible systems have been determined.