It is shown that chitosan gel beads are suitable carriers of 8-hydroxy-7-iodoquinoline-5-sulfonic acid (SQ) and 2,5-dihydroxybenzenesulfonic acid (DHBSA)- substances applied in medicine. Drug release has been investigated with respect to the nature of the crosslinking agent (epichlorohydrin or glutaraldehyde) and pH of the medium. Considerable differences in the release rate of DHBSA and SQ have been found. The total amount of the desorbed SQ, as well as the release rate of the drug depends on pH of the medium - they decrease from alkaline to acidic medium. The antimicrobial and antimycotic activity of the loaded with SQ beads is demonstrated.