The wet grinding of materials in most industrial grinding devices can be significantly influenced by controlled changes in slurry rheology. Thus, pulp density, the level of fines present, and the pulp chemistry conditions are all very important to maximizing throughput. This paper will present a brief summary of what grinding studies involving slurry rheology control have shown industrially followed by a summary of the nature of dispersant chemical adsorption behavior for different materials. Finally, a summary of the attributes of various chemical families used industrially as wet grinding additives is given to assist industrial practitioners.