화학공학소재연구정보센터
Applied Microbiology and Biotechnology, Vol.48, No.5, 630-635, 1997
The Influence of a Specific Microelemental Environment in Alginate Gel Beads on the Course of Propionic-Acid Fermentation
In this work the exchange of calcium, cobalt, iron, magnesium, zinc and manganese ions between alginate gel beads and casein medium was investigated. The high release of calcium ions from alginate to the medium and the biosorption of some metal ions were observed. The pure alginate gel adsorbed all the metal ions examined, from a fermentative medium. Gel with immobilized cells of two strains of Propionibacterium freudenreichii subsp, shermanii showed an active ability to adsorb only cobalt, iron and zinc ions. In this way, a special microelemental environment was created in the alginate gel. This resulted in an increase of propionic acid production and a decrease of vitamin B-12 biosynthesis.