Resin (RPPBD) prepared by Friedel-Craft＇s polycondensation of 2,4-dihydroxypropiophenone with 1,4-butane diol in the presence of polyphosphoric acid catalyst proved to be a selective ion-exchange resin and indicates coordination tendency for some metal ions. The resin was characterized by elemental analysis, IR spectra, viscosity study and its number average molecular mass (($) over bar M(n)) was determined by non-aqueous titration and found to be 2475 g/mol. Chelation ion-exchange properties of this resin have also been studied employing batch equilibration method. It was employed to study selectivity of metal ion uptake over a wide pH range and in media of various ionic strength. The overall rate of metal uptake follows the order: UO22+ > Fe3+ > CU2+ > Ni2+.