At the Radiochemical Engineering Development Center (REDC), irradiated targets are processed for the recovery of valuable radioisotopes, principally transuranium nuclides. A system was recently installed for treating the various liquid alkaline waste streams for removal of excess radioactive contaminants at REDC. Radionuclides that are removed will be stored as solids, and thus the future discharge of radionuclides to liquid-low level waste tank storage will be greatly reduced. The treatment system is of modular design and is installed in a hot cell at REDC, where preliminary testing is in progress. The module incorporates the following: (1) a resorcinol-formaldehyde resin column for cesium removal, (2) a cross-flow filtration unit for removal of rare earths and actinides as hydroxide, and (3) a waste solidification unit. Process flowsheets for operation of the module, key features of the module design, and its computer-assisted control system are presented. Good operability of the cross-flow filter system is mandatory to the: successful treatment of REDC wastes. Results of tests to date on the operation of the filter in its slurry collection mode and its slurry washing mode are presented. These tests include the effects of entrained organic solvent in the waste stream to the filter.