Cyclophane-mediated transport of two- or three-ring aromatic compounds across aqueous supported liquid membranes (SLMs) was investigated. SLMs containing water-soluble cyclophanes, OCP44 and 66, exhibited facilitated transport for aromatic compounds but not for aliphatic compounds. The flux of 2,6-dimethylnaphthalene was decreased with an increase of membrane thickness, indicating that the rate-determining step of the present cyclophane-mediated transport is the diffusion process of the carrier-solute complex in the membrane. The SLMs showed isomer-selectivity for methylnaphthalenes (MNs), ethylnaphthalenes (ENs), dimethylnaphthalenes (DMNs), and three-ring aromatic compounds. The isomer-selectivity of QCP44 was completely opposite to that of QCP66; the flux order of QCP44 was 2-MN > 1-MN, 2-EN > 1-EN, 2,6-DMN > 1,5-DMN and anthracene > phenanthrene; and that of QCP66 was 1-MN > 2-MN, 1-EN > 2-EN, 1,5-DMN > 2,6-DMN and phenanthrene > anthracene. This difference in flux was discussed in terms of the cyclophane-involved complex formation.