A series of samples Pr0.6-xSr0.4MnO3 (x = 0, 0.01, 0.05, 0.1, 0.15, 0.2) were synthesized by a solid state reaction method. Pr deficiency at the A site has a great effect on the properties of Pr0.6-xSr0.4MnO3 as the cathode of SOFCs (solid oxide fuel cells). Compared to the commonly used La0.6Sr0.4MnO3 and La0.55Sr0.4MnO3 cathode, Pr0.6-xSr0.4MnO3 is better in the properties of conductivity, overpotential and impedance. In all the samples, the one with x = 0.05, Pr0.55Sr0.4MnO3, revealed the best performance in the measured temperature range.