Flexible PVC is widely used in the medical industry in a wide variety of applications. In numerous instances, the material needs to sustain stresses at subambient temperatures. Dynamic mechanical analysis was correlated with product performance. It was found that the location of the T-g was the most important factor. However, impact studies indicated brittle-to-ductile transitions well below the T-g most likely originating from sub-T-g secondary transitions. Further mapping of the product survival probability onto the impact spectrum allowed additional insights into the performance. Good agreement was also obtained with a method to predict the impact spectrum with DMA data.