In order to simplify the thermo-kinetic research method and study faster reactions, two novel thermo-kinetic research methods, namely the thermo-analytical analog curve and characteristic parameter methods, have been proposed in this paper. The general formulae for calculating kinetic parameter K-n and rate constant k(n) have been derived. The thermo-kinetics of five reactions with first, second, third, and fractional orders, respectively, have been studied with these methods, and their validity has been verified by the experimental results.