An algorithm for design and analysis of crystallization processes with electrolyte systems is presented. This algorithm consists of a thermodynamic part, a synthesis part and a design part. The three parts are integrated through a simulation engine. The main features of the algorithm is the use of thermodynamic insights not only to generate process alternatives but also to obtain good initial estimates for the simulation engine and for visualization of process synthesis/design. The main steps of the algorithm are highlighted through a case study involving an industrial crystallization process.