Methods for developing different types of organic chemical technologies have been elaborated. It required the building up of a system that integrates the advantages of a reaction calorimeter and a model of industrial controlled reactors. The hardware and software configuration support the transfer of elaborated control programs of reactions from laboratory level to the industrial technology. The results of application are shown through the examples of typical unit processes of organic chemical technologies like alkylation, diazotization and esterification in which economical, environmental and chemical advantages could be realized, respectively.