화학공학소재연구정보센터
Biotechnology Letters, Vol.17, No.2, 219-224, 1995
Citric-Acid and Polyols Production by Aspergillus-Niger at High Glucose-Concentration in Solid-State Fermentation on Inert Support
Aspergillus niger cultures at high initial glucose concentration (up to 400 g/l) on Amberlite as inert support were carried out. Citric acid was accumulated in the support showing high concentration (94.54 g/l) and productivity (1.35 g/l h) without inhibition related to the presence of metals (Mn2+, Zn2+, Co2+, Cu2+, and Ca2+) at high concentrations. Citric acid accumulation was clearly associated with both, glycerol production and to the age of the culture. Glycerol and erythritol, the major osmoregulator metabolites, were also produced (8.16 and 24.57 g/l respectively) at 400 gn of glucose.