The bioaccumulation of metal chlorides (Cu, Zn, Co, Cd, Ni and Cr) to immobilised S. cerevisiae was studied in packed-bed continuous flow columns. The metals were eluted from the columns using 0.1 M HCl, with a desorption of greater than or equal to 90 % being attained. Reusability of the biomass was demonstrated. Mixed metal solutions were applied and selective binding and recovery was achieved between copper and cobalt.