The effects of earthworm-processed pig manure (vermicompost) on germination, growth, and yields of tomato (Lycopersicon esculentum Mill.) plants were evaluated under glasshouse conditions. Tomatoes were germinated and grown in a standard commercial greenhouse container medium (Metro-Mix 360), substituted with 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100% (by volume) pig manure vermicompost. The control consisted of Metro-Mix 360 alone without vermicompost. Plants were grown for 158 days and were frequently supplied with a complete mineral nutrient solution. The germination rates of tomato seeds increased significantly upon substitution of Metro-Mix 360 with 20%, 30%, and 40% vermicompost. Seedlings grown in 100% pig manure vermicompost were significantly shorter, had fewer leaves, and weighed less than those in Metro-Mix 360 controls. Incorporation of 10% or 50% vermicompost into Metro-Mix 360 increased the dry weights of tomato seedlings significantly compared to those grown in the Metro-Mix 360 controls. The largest marketable yield was in the substitution of Metro-Mix 360 with 20% vermicompost (5.1 kg/plant). The average weight of a tomato fruit in substitution of Metro-Mix 360 with 20% vermicompost was 12.4% greater than that in the Metro-Mix 360 control. Substitution of Metro-Mix 360 with 10%, 20%, and 40% vermicompost reduced the proportions of fruits that were non-marketable, and produced more large size (diameter > 6.4 cm) than small size (diameter < 5.8 cm) tomato fruits. Then was no significant difference in overall tomato yields between Metro-Mix 360 and 100% pig manure vermicompost. Some of the growth and yield enhancement resulting from substitution of Metro-Mix 360 with pig manure vermicompost could be attributed to the high mineral N concentration of the pig manure vermicompost. However, other factors might have also been involved since all plants were frequently supplied with all required nutrients. These factors need to be investigated in future studies.