Biotechnology Letters, Vol.18, No.5, 571-576, 1996
Enantioselective Oxidations by the Diketocamphane Monooxygenase Isozymes from Pseudomonas-Putida
2,5-Diketocamphane 1,2-monooxygenase and 3,6-diketocamphane 1,6-monooxygenase isolated from (+/-)-camphor grown Pseudomonas putida NCIMB 10007 catalysed two different types of Baeyer-Villiger oxidations. The former isozyme biotransformed various bicyclic [3.2.0] ketones and aryl alkyl sulfides with consistently greater regio- and/or enantioselectivity, yielding lactone and sulfoxide products with enantiomeric excesses > 55%.