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Biotechnology Letters, Vol.21, No.6, 467-479, 1999
Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals
The technology of large-scale plant cell culture is feasible for the industrial production of plant-derived fine chemicals. Due to low or no productivity of the desired compounds the economy is only in a few cases favorable. Various approaches are studied to increase yields, these encompass screening and selection of high producing cell lines, media optimization, elicitation, culturing of differentiated cells (organ cultures), immobilization. In recent years metabolic engineering has opened a new promising perspectives for improved production in a plant or plant cell culture.
Keywords:EXPRESSING TRYPTOPHAN DECARBOXYLASE;CELL-SUSPENSION-CULTURES;CATHARANTHUS-ROSEUS;ALKALOID PRODUCTION;ANTHRANILATESYNTHASE;ISOPENTENYL DIPHOSPHATE;ISOPRENOID BIOSYNTHESIS;STRICTOSIDINE SYNTHASE;TRANSCRIPTION FACTORS;NICOTIANA-TABACUM