An experimental analysis of heat transfer and resin reaction in flow through fiber reinforcement is presented. The results from non-isothermal mold filling experiments with and without resin reaction are compared with those from numerical simulation based on a mixed Eulerian-Langrangian approach. Heat transfer between the fluid and the fiber reinforcement is investigated using both one-temperature and two-temperature models with the thermal dispersion effect included. The prediction of the two-temperature model is shown to be in good agreement with experimental results.